Developed through 7+ years of R&D, NOVOS Core is the first to be designed around the 12 biological hallmarks of aging—a coordinated, multi-pathway approach—and the complete formulation has been evaluated in a randomized, double-blind, placebo-controlled human clinical study, not just individual ingredient studies.
Developed through 7+ years of R&D, NOVOS Core is the first to be designed around the 12 biological hallmarks of aging—a coordinated, multi-pathway approach—and the complete formulation has been evaluated in a randomized, double-blind, placebo-controlled human clinical study, not just individual ingredient studies.
Healthy Aging
Vascular Function & Circulation
Cellular Energy & Metabolism
Cognitive Function & Mental Clarity
Skin Health & Cellular Resilience
Sleep Quality & Mood Balance
Healthy Aging
Vascular Function & Circulation
Cellular Energy & Metabolism
Cognitive Function & Mental Clarity
Skin Health & Cellular Resilience
Sleep Quality & Mood Balance
An all-in-one longevity formulation, designed to support the biological systems that influence how we age—today and over time.
NOVOS Core is a daily longevity formulation built as a biological pathway-informed system—not a stack, trend, or influencer routine.
Developed over 7+ years with scientists and academic collaborators, it was designed as a complete system—to address all 12 Hallmarks of Aging simultaneously.
Unlike products built by combining individually studied ingredients, NOVOS Core has been evaluated as a unified formulation across mechanistic research, aged-animal lifespan research, and a rigorously designed randomized, double-blind, placebo-controlled human clinical study.
Aging science has identified 12 core biological processes that drive functional decline over time. NOVOS Core was designed to address all of them simultaneously.
Mitochondria are crucial for energy production in cells; their dysfunction leads to decreased energy and cellular/organ aging. Malate and Calcium Alpha-Ketoglutarate enhance mitochondrial function and energy output.
Cells that cease to divide accumulate as senescent or “zombie” cells, contributing to aging and tissue degradation. Fisetin helps clear these cells, rejuvenating tissues and enhancing cellular function.
Proteostasis involves maintaining cell function by ensuring proteins fold and function properly. Loss of proteostasis leads to diseases and aging. Glycine and Hyaluronic Acid aid in maintaining protein integrity and function.
Effective communication between cells diminishes with age, leading to increased inflammation and cellular decline. L-Theanine and Glucosamine help maintain cellular communication, enhancing adaptability and resilience.
Increased accumulation of DNA damage contributes to aging and the development of age-related diseases. Pterostilbene and Magnesium help protect DNA, maintaining genomic stability.
Changes in epigenetic control of gene expression can lead to dysfunction and aging. Vitamin C and Calcium Alpha-Ketoglutarate have beneficial effects on epigenetic regulation, promoting healthier aging.
Telomeres protect the ends of chromosomes, and their shortening through repeated cell divisions leads to cell aging and death. Pterostilbene and Microdosed Lithium support the maintenance of telomere length, enhancing cellular longevity.
Aging affects the body’s ability to sense and respond to nutrients, impacting metabolism properly and growth pathways. Fisetin and Malate play a critical role in regulating these nutrient-sensing pathways.
With age, stem cells’ regenerative capacity diminishes, impairing the body’s ability to repair and regenerate tissues. Glycine and Calcium Alpha-Ketoglutarate support stem cell function and regenerative capacity.
Macroautophagy involves the degradation and recycling of cellular debris and dysfunctional components; its decline is linked to aging. Glucosamine and Fisetin promote the autophagic process, aiding cellular renewal and longevity.
Chronic, low-grade inflammation increases with age, contributing significantly to the progression of age-related diseases. Ginger and Pterostilbene mitigate inflammation, enhancing cellular health and longevity.
An imbalance in the gut microbiome can lead to a host of health issues and is linked to aging. Rhodiola rosea and Fisetin support a healthy gut microbiome, promoting overall well-being.
Each ingredient in NOVOS Core was selected not in isolation, but for how it interacts within a larger biological system.
The formulation was designed to maximize synergistic effects and minimize antagonistic interactions across aging pathways, and evaluated as a complete system rather than inferred from individual ingredients.
Designed by leading doctors and scientists specializing in aging, NOVOS Core is rooted in modern aging biology and informed by clinical research.
Our 100% vegan, sugar-free, and gluten-free formula meets high standards for purity, tolerability, and long-term use.
Independently verified by third-party laboratories to confirm purity, potency, and consistency.
Manufactured in the U.S.A. using rigorously tested ingredients sourced from trusted partners worldwide.
Designed by leading doctors and scientists specializing in aging, NOVOS Core is rooted in modern aging biology and informed by clinical research.
Our 100% vegan, sugar-free, and gluten-free formula meets high standards for purity, tolerability, and long-term use.
Independently verified by third-party laboratories to confirm purity, potency, and consistency.
Manufactured in the U.S.A. using rigorously tested ingredients sourced from trusted partners worldwide.
Evidence supporting NOVOS Core as a rigorously studied longevity formulation — evaluated across mechanistic research, animal lifespan studies, and a placebo-controlled human clinical trial.
In a recent study of aged mice, NOVOS Core increased lifespan by 18%, surpassing all previously studied supplements in similar research, including NAD+ boosters like nicotinamide riboside.
In just 6 months, 73% of NOVOS Core and NOVOS Boost users experienced a significant reduction in their biological aging pace, with an average slowdown of 8.7% which works out to be 31.75 days younger per year. Nobody’s aging sped up.
In human cell cultures, ingredients in the formulation were associated with a 50% reduction in markers of cellular senescence.
After 6 months, benefits to skin firmness were observed in participants, with an average increase of 22%., enhancing both appearance and feel.
NOVOS Core users ranked (#2, #5, and #7) for lowest rates of aging in a global competition that uses the DunedinPACE algorithm created by Duke and Columbia scientists to measure epigenetic changes.
Ingredients in NOVOS Core were able to prevent DNA damage by up to 77% in skin cells exposed to irradiation (e.g., UV rays) in an in-vitro study. In human skin cell studies, the ingredients were associated with markers of genomic stability under conditions of cellular stress.
NOVOS Core’s ingredients reduced unwanted cell death processes called oxytosis/ferroptosis, by 50%, while also support for healthy inflammatory response, in an in-vitro human cellular study.
In a recent study of aged mice, NOVOS Core increased lifespan by 18%, surpassing all previously studied supplements in similar research, including NAD+ boosters like nicotinamide riboside.
In just 6 months, 73% of NOVOS Core and NOVOS Boost users experienced a significant reduction in their biological aging pace, with an average slowdown of 8.7% which works out to be 31.75 days younger per year. Nobody’s aging sped up.
In human cell cultures, ingredients in the formulation were associated with a 50% reduction in markers of cellular senescence.
After 6 months, benefits to skin firmness were observed in participants, with an average increase of 22%., enhancing both appearance and feel.
NOVOS Core users ranked (#2, #5, and #7) for lowest rates of aging in a global competition that uses the DunedinPACE algorithm created by Duke and Columbia scientists to measure epigenetic changes.
Ingredients in NOVOS Core were able to prevent DNA damage by up to 77% in skin cells exposed to irradiation (e.g., UV rays) in an in-vitro study. In human skin cell studies, the ingredients were associated with markers of genomic stability under conditions of cellular stress.
NOVOS Core’s ingredients reduced unwanted cell death processes called oxytosis/ferroptosis, by 50%, while also support for healthy inflammatory response, in an in-vitro human cellular study.
In human clinical research, NOVOS Core demonstrated measurable biological effects — with broader functional benefits emerging progressively over time.
Feel a noticeable boost in daily energy levels and a more stable, balanced mood as cellular repair begins.
Experience improved skin hydration and elasticity as cellular rejuvenation enhances overall skin health.
Sharper focus, enhanced memory, and improved cognitive performance.
Measurable improvement in biological aging, supported by improved DNA repair, mitochondrial function, and more.
Designed to support the biological systems that influence how we age — delivering early benefits and long-term support for resilience over time.
NOVOS Core has been reviewed by scientists working at the forefront of aging biology — including researchers from Harvard, MIT, and leading longevity institutions.
What stood out was the seriousness of the scientific framework — mechanistic grounding, preclinical data, and an emerging human evidence base — combined with a commitment to rigorous evaluation.” — Dr. Doina Kulick, MD Lead Physician, Longevity Medicine, Mayo Clinic Arizona
Built from aging biology. Validated in living systems.
Clinically Validated Formulation
3rd-Party
Tested
Sugar-Free & Gluten-Free
Clinically Relevant Doses
Vegan & Clean Label
Backed by controlled human and preclinical research
NOVOS Core is rated 4.8 out of 5 stars. We have collected 1331 ratings.
I’m 61 w/ chronic inflammation. Moving back to a colder climate moved me from less active to downright wanting to quit. I had to lean and hold on to railings, & the chronic pain in my hips, knees, hands & feet were making movement intolerable, so much so, I chose to sit more and more. In my quest for answers for anti-inflammatory care/cures, I stepped into the longevity world; something I balked at. After reading some testimonies on your product I decided to give them a try. I wish I had started them separately-but I took Core and Vital at the same time. On day 6, I got out of bed, and flew down the stairs…midway down I realized I didn’t need to hold on to the rail. And I ran up the stairs to be sure…*there may be permanent damage from the years of inflammation. It has been 9 days. I am almost pain free. I ate badly one day and thought I’d pay for it. I didn’t feel as good but wanted to see if this was just the improved food or the NOVOS. I am not going to “test” anymore. With NOVOS Core and Vital, I am not going to take this for granted. I am going to continue to improve my diet and exercise and see just how much healthier and stronger I can get! I am more focused, excited about life and my future. I am hoping more improvements will come. If they do, I’ll be sure to let you know. So grateful for the brave scientists who work with integrity to help humans live the rich life God intended for His kids. God bless you!
Fantastic product and fantastic customer service! I highly recommend the NOVOS line. I’ve been taking them for 6 months and can see (skin) and feel (energy levels, sense well being) the difference. Also, I prefer the Orange flavored Core vs the unflavored version.
Amazing product. I have a very senstive Gut. I always bloated after eating or without eating any
meal. When if i feel bloated i drink novos core it helps me a lot !! my Gut starts to digest better!! I feel my brain functions better because no more bloating!!!
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Individual experiences may vary and are distinct from results observed in controlled clinical research.
The primary longevity ingredients are:
Other natural ingredients: Erythritol*, Malic Acid, Natural Flavors, Sodium Bicarbonate, Silicon Dioxide, Calcium Silicate*, Stevia*
*ingredients only in Orange, not in Unflavored
NOVOS Core is calorie free and sugar free. No artificial colors, preservatives or additives. Suitable for vegans. Non-GMO.
The focus is on the long-term. Remember that the key benefits of achieving maximum lifespan potential may not be perceived on a daily basis, as it impacts biology over time with consistent daily use on your Longevity Journey.
Many customers report seeing or feeling a noticeable benefit within 30 days. However, everyone’s body is different, and the benefits you may see or feel (skin health, energy, mood, etc.) are often just the most visceral ones.
Some people feel results in as a little as 7 days due to specific benefits like skin health and cognitive support.
Other longer term benefits like mitochondrial health and genomic stability may take longer, or you may not notice anything at all. That’s completely normal.
As long as you continue your daily intake, those beneficial nutrients are doing their work inside to optimize your health.
NOVOS Core is meant for early-adult, middle-aged and elderly people. It is developed to slow down aging, a process that already starts from a young age. The most pronounced short-term effects will be noticed by older people, while the greatest long-term longevity benefits will come from starting at a younger age.
NOVOS Core is free from:
It adheres to the following diets:
NOVOS Core is safe to take with other supplements.
There are no known contraindications with NOVOS Core and any over-the-counter or prescription medications, though we encourage you to double check with your physician before adding our product to your regimen.
If you are already taking any ingredients found in the NOVOS Core formulation, such as magnesium or Vitamin C, you can consider discontinuing those supplements and simplifying your routine with NOVOS Core.
A small percentage of users (less than 3%) report that they feel stomach discomfort when they first start taking NOVOS. This is normal: when a new food is introduced into your routine, it can take time for your microbiome and digestive tract to adapt.
If this is the case for you, we recommend the following:
Try steps 1-3 for a few weeks. In 90% of cases, the issue resolves itself. If it does not for you, feel free to contact our customer care team.
To our knowledge, we don’t see a problem with taking NOVOS during pregnancy. However, given that this is a very critical period in the development of your child, and given that there could be unknown unknowns, we recommend that you err on the side of caution. That is, we advise against taking NOVOS while pregnant (and while breastfeeding).
Short answer: no. No refrigeration needed. Storing at room temperature in a cool, dry environment is perfect for NOVOS Core.
For monthly subscriptions, your order will contain 1 box of NOVOS Core. For prepaid options (6 or 12 months), you will receive all 6 or 12 boxes upfront.
If you have active subscriptions to any NOVOS products, you can change the renewal date, cancel or renew your subscriptions at any time, as often as you would like. If you wish to choose a different renewal date or cancel a subscription, it must be done at least 2 business days prior to the renewal date, otherwise the transaction will be considered complete.
Keep in mind that every person’s body is different, and the short-term benefits you see or feel (skin health, energy, sleep, mood, etc.) should be considered as added benefits. As long as you continue your daily intake, the beneficial nutrients are doing their work inside to optimize your health. Consistent use is the key to slowing down your aging to be YoungerForLonger™.
US-based purchases: If you still wish to return your NOVOS products (Core and/or Boost), it must be within thirty (30) days and each product must be unopened (still sealed). We never charge consumers shipping fees as we pay for the costs, and we will provide a prepaid return shipping label, so there will be a deduction of $25 per transaction to cover the back and forth shipping costs. There will also be a restocking fee of $35 per transaction (deductions will not exceed the value of the order). If you would like a NOVOS credit instead of a refund to your original payment method, we will waive the shipping and restocking fees ($60). NOVOS credit must be used within 1 year of issuance. All purchases of NOVOS Age are final.
Non-US-based purchases: All international orders are final for all products.
NOVOS is not responsible for any lost packages that were incorrectly addressed due to customer error. We generate shipping labels from the information the customer provides, so if you enter an incorrect or incomplete address (e.g., incorrect zip code, missing apartment/office number) and your package is lost, NOVOS is not responsible. We appreciate your understanding.
If you input the incorrect address on your order and it has only just begun processing, try to cancel the order immediately by logging into your account. If you are unsure if this processed correctly, immediately email us at care@novoslabs-development.mystagingwebsite.com with the new address information. Then, place your order again using the correct address. However, once your package is processed and shipped, we cannot make any more modifications to your shipment.
We guarantee that our products will ship to you in excellent condition without any defects and we will replace the product free of charge within 30 days of purchase if the boxes or bottles come damaged. All NOVOS products undergo thorough quality assurance to ensure they meet our high standards. However, if you find a damaged or defective product upon arrival due to mishandling during shipping, you must submit a claim within 2 days of receiving your order. To create a claim, please email us at care@novsolabs.com and include:
**Please keep all products and packaging as we may ask you to ship all defective products to us for additional inspection. If you do not complete this step, your claim may be denied.
This return policy applies only to purchases made through www.novoslabs-development.mystagingwebsite.com. If you purchased NOVOS products through a third-party marketplace and want to make a return, please contact that third-party marketplace.
Yes. While you can’t change the number of birthdays that have passed (chronological age), it is possible to slow down or accelerate your biological age based upon lifestyle changes.
